Fixed tissue research

Representative publications related to the resource

Baizer JS, Witelson SF. 2023. Comparative analysis of four nuclei in the human brainstem: Individual differences, left-right asymmetry, species differences. Front Neuroanat. 17:1069210.

Alhelo H, Dogiparthi J, Baizer JS, Hof PR, Sherwood CC, Kulesza R. 2023. Characterization of the superior olivary complex of chimpanzees (Pantroglodytes) in comparison to humans. Hear Res. 430:108698.

Edler MK, Munger EL, Maycon H, Hopkins WD, Hof PR, Sherwood CC, Raghanti MA. 2023. The association of astrogliosis and microglial activation with aging and Alzheimer's disease pathology in the chimpanzee brain. J Neurosci Res. 101(6):881-900.

Munger EL, Edler MK, Hopkins WD, Hof PR, Sherwood CC, Raghanti MA. 2022. Comparative analysis of astrocytes in the prefrontal cortex of primates: Insights into the evolution of human brain energetics. J Comp Neurol. 530(18):3106-3125.

Reyes LD, Do Kim Y, Issa H, Hopkins WD, Mackey S, Sherwood CC. 2023. Cytoarchitecture, myeloarchitecture, and parcellation of the chimpanzee inferior parietal lobe. Brain Struct Funct. 228(1):63-82.

Falcone C, McBride EL, Hopkins WD, Hof PR, Manger PR, Sherwood CC, Noctor SC, Martínez-Cerdeño V. 2022. Redefining varicose projection astrocytes in primates. Glia. 70(1):145-154.

Rogers Flattery CN, Coppeto DJ, Inoue K, Rilling JK, Preuss TM, Young LJ. 2022. Distribution of brain oxytocin and vasopressin V1a receptors in chimpanzees(Pan troglodytes): comparison with humans and other primate species. Brain Struct Funct. 227(5):1907-1919.

Hirter KN, Miller EN, Stimpson CD, Phillips KA, Hopkins WD, Hof PR, Sherwood CC, Lovejoy CO, Raghanti MA. 2021. The nucleus accumbens and ventral pallidum exhibit greater dopaminergic innervation in humans compared to other primates. Brain Struct Funct. 226(6):1909-1923.

Falcone C, Penna E, Hong T, Tarantal AF, Hof PR, Hopkins WD, Sherwood CC, Noctor SC, Martínez-Cerdeño V. 2021. Cortical Interlaminar Astrocytes Are Generated Prenatally, Mature Postnatally, and Express Unique Markers in Human and Nonhuman Primates. Cereb Cortex. 31(1):379-395. 

Amiez C, Sallet J, Novek J, Hadj-Bouziane F, Giacometti C, Andersson J, Hopkins WD, Petrides M. 2021. Chimpanzee histology and functional brain imaging show that the paracingulate sulcus is not human-specific. Commun Biol. 4(1):54.

La Rosa C, Cavallo F, Pecora A, Chincarini M, Ala U, Faulkes CG, Nacher J, Cozzi B, Sherwood CC, Amrein I, Bonfanti L. 2020. Phylogenetic variation in cortical layer II immature neuron reservoir of mammals. Elife. 9:e55456.

Sherwood CC, Miller SB, Karl M, Stimpson CD, Phillips KA, Jacobs B, Hof PR, Raghanti MA, Smaers JB. 2020. Invariant Synapse Density and Neuronal Connectivity Scaling in Primate Neocortical Evolution. Cereb Cortex. 30(10):5604-5615.

Staes N, Smaers JB, Kunkle AE, Hopkins WD, Bradley BJ, Sherwood CC. 2019. Evolutionary divergence of neuroanatomical organization and related genes in chimpanzees and bonobos. Cortex. 118:154-164.

Munger EL, Edler MK, Hopkins WD, Ely JJ, Erwin JM, Perl DP, Mufson EJ, Hof PR, Sherwood CC, Raghanti MA. 2018. Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees. J Comp Neurol. 527(7):1179-1195.

Falcone C, Wolf-Ochoa M, Amina S, Hong T, Vakilzadeh G, Hopkins WD, Hof PR, Sherwood CC, Manger PR, Noctor SC, Martínez-Cerdeño V. 2018. Cortical interlaminar astrocytes across the therian mammal radiation. J Comp Neurol. doi: 10.1002/cne.24605.

Issa HA, Staes N, Diggs-Galligan S, Stimpson CD, Gendron-Fitzpatrick A, Taglialatela JP, Hof PR, Hopkins WD, Sherwood CC. 2018. Comparison of bonobo and chimpanzee brain microstructure reveals differences in socio-emotional circuits. Brain Struct Funct. 224(1):239-251.

Edler MK, Sherwood CC, Meindl RS, Munger EL, Hopkins WD, Ely JJ, Erwin JM, Perl DP, Mufson EJ, Hof PR, Raghanti MA. 2018. Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees. J Comp Neurol. 526(18):2921-2936. 

Raghanti MA, Edler MK, Stephenson AR, Munger EL, Jacobs B, Hof PR, Sherwood CC, Holloway RL, Lovejoy CO. 2018. A neurochemical hypothesis for the origin of hominids. Proc Natl Acad Sci U S A. 115(6):E1108-E1116. 

Baizer JS, Wong KM, Salvi RJ, Manohar S, Sherwood CC, Hof PR, Baker JF, Witelson SF. 2018. Species Differences in the Organization of the Ventral Cochlear Nucleus. Anat Rec. 301(5):862-886. 

Baizer JS, Wong KM, Sherwood CC, Hof PR, Witelson SF. 2018. Individual variability in the structural properties of neurons in the human inferior olive. Brain Struct Funct. 223(4):1667-1681.

Rogers CN, Ross AP, Sahu SP, Siegel ER, Dooyema JM, Cree MA, Stopa EG, Young LJ, Rilling JK, Albers HE, Preuss TM. 2018. Oxytocin- and arginine vasopressin-containing fibers in the cortex of humans, chimpanzees, and rhesus macaques. Am J Primatol. 80(10):e22875. 

Edler MK, Sherwood CC, Meindl RS, Hopkins WD, Ely JJ, Erwin JM, Mufson EJ, Hof PR, Raghanti MA. 2017. Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease. Neurobiol Aging, 59:107-120

Stephenson AR, Edler MK, Erwin JM, Jacobs B, Hopkins WD, Hof PR, Sherwood CC, Raghanti MA. 2017. Cholinergic innervation of the basal ganglia in humans and other anthropoid primates. J Comp Neurol, 525(2):319-332

Hopkins WD, Stimpson CD, Sherwood CC. 2017. Social cognition and brain organization in chimpanzees (Pan troglodytes) and bonobos (Pan paniscus). In B. Hare & S. Yamamoto (Eds), Bonobos: Unique in Mind, Brain and Behavior. Oxford University Press. 

Gilissen EP, Leroy K, Yilmaz Z, Kövari E, Bouras C, Boom A, Poncelet L, Erwin JM, Sherwood CC, Hof PR, Brion JP. 2016. A neuronal aging pattern unique to humans and common chimpanzees. Brain Struct Funct, 221(1): 647-64

Raghanti MA, Edler MK, Stephenson AR, Wilson LJ, Hopkins WD, Ely JJ, Erwin JM, Jacobs B, Hof PR, Sherwood CC. 2016. Human-specific increase of dopaminergic innervation in a striatal region associated with speech and language: A comparative analysis of the primate basal ganglia. J Comp Neurol, 524(10):2117-29

Stimpson CD, Barger N, Taglialatela JP, Gendron-Fitzpatrick A, Hof PR, Hopkins WD, Sherwood CC. 2016. Differential serotonergic innervation of the amygdala in bonobos and chimpanzees. Soc Cogn Affect Neurosci, 11(3): 413-422

Phillips KA, Stimpson CD, Smaers JB, Raghanti MA, Jacobs B, Popratiloff A, Hof PR, Sherwood CC. 2015. The corpus callosum in primates: processing speed of axons and the evolution of hemispheric asymmetry. Proc Biol Sci, 282(1818):20151535

Raghanti MA, Edler MK, Meindl RS, Sudduth J, Bohush T, Erwin JM, Stimpson CD, Hof PR, Sherwood CC. 2014. Humans and great apes share increased cortical neuropeptide Y innervation compared to other haplorrhine primates. Front Hum Neurosci, 8:101. doi: 10.3389/fnhum.2014.00101

Baizer JS, Paolone NA, Sherwood CC, Hof PR. 2013. Neurochemical organization of the vestibular brainstem in the common chimpanzee (Pan troglodytes). Brain Struct Funct, 218(6): 1463-85

Bauernfeind AL, de Sousa AA, Avasthi T, Dobson SD, Raghanti MA, Lewandowski AH, Zilles K, Semendeferi K, Allman JM, Craig AD, Hof PR, Sherwood CC. 2013. A volumetric comparison of the insular cortex and its subregions in primates. J Hum Evol, 64: 263-279

Bianchi S, Stimpson CD, Bauernfeind AL, Schapiro SJ, Baze WB, McArthur MJ, Bronson E, Hopkins WD, Semendeferi K, Jacobs B, Hof PR, Sherwood CC. 2013. Dendritic morphology of pyramidal neurons in the chimpanzee neocortex: regional specializations and comparison to humans. Cereb Cortex, 23(10): 2429-36

Bianchi S, Stimpson CD, Duka T, Larsen MD, Janssen WG, Collins Z, Bauernfeind AL, Schapiro SJ, Baze WB, McArthur MJ, Hopkins WD, Wildman DE, Lipovich L, Kuzawa CW, Jacobs B, Hof PR, Sherwood CC. 2013. Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex resembles humans. Proc Natl Acad Sci U S A, 110 Suppl 2: 10395-401

Teffer K, Buxhoeveden DP, Stimpson CD, Fobbs AJ, Schapiro SJ, Baze WB, McArthur MJ, Hopkins WD, Hof PR, Sherwood CC, Semendeferi K. 2013. Developmental changes in the spatial organization of neurons in the neocortex of humans and common chimpanzees. J Comp Neurol, 521 (18): 4249-59

Bryant KL, Suwyn C, Reding KM, Smiley JF, Hackett TA, Preuss TM. 2012. Evidence for ape and human specializations in geniculostriate projections from VGLUT2 immunohistochemistry. Brain Behav Evol, 80(3):210-21

Miller DJ, Duka T, Stimpson CD, Schapiro SJ, Baze WB, McArthur MJ, Fobbs AJ, Sousa AM, Sestan N, Wildman DE, Lipovich L, Kuzawa CW, Hof PR, Sherwood CC. 2012. Prolonged myelination in human neocortical evolution. Proc Natl Acad Sci U S A, 109(41): 16480-5

Spocter MA, Hopkins WD, Barks SK, Bianchi S, Hehmeyer AE, Anderson SM, Stimpson CD, Fobbs AJ, Hof PR, Sherwood CC. 2012. Neuropil distribution in the cerebral cortex differs between humans and chimpanzees. J Comp Neurol, 520(13): 2917-29

Spocter MA, Hopkins WD, Garrison AR, Bauernfeind AL, Stimpson CD, Hof PR, Sherwood CC. 2010. Wernicke's area homologue in chimpanzees (Pan troglodytes) and its relation to the appearance of modern human language. Proc Biol Sci, 277(1691): 2165-74

Schenker NM, Hopkins WD, Spocter MA, Garrison AR, Stimpson CD, Erwin JM, Hof PR, Sherwood CC. 2010. Broca's area homologue in chimpanzees (Pan troglodytes): probabilistic mapping, asymmetry, and comparison to humans. Cereb Cortex, 20(3): 730-42

Rosen RF, Farberg AS, Gearing M, Dooyema J, Long PM, Anderson DC, Davis-Turak J, Coppola G, Geschwind DH, Paré JF, Duong TQ, Hopkins WD, Preuss TM, Walker LC. 2008. Tauopathy with paired helical filaments in an aged chimpanzee. J Comp Neurol, 509(3):259-70

Cola MG, Seltzer B, Preuss TM, Cusick CG. 2005. Neurochemical organization of chimpanzee inferior pulvinar complex. J Comp Neurol, 484(3):299-312

Preuss TM, Coleman GQ. 2002. Human-specific organization of primary visual cortex: alternating compartments of dense Cat-301 and calbindin immunoreactivity in layer 4A. Cereb Cortex, 12(7):671-91

Hackett TA, Preuss TM, Kaas JH. 2001. Architectonic identification of the core region in auditory cortex of macaques, chimpanzees, and humans. J Comp Neurol, 441(3):197-222

National Chimpanzee Brain Resoure is supported by NIH - National Institute of Neurological Disorders and Stroke


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